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Fully Automated HDX-MS at Your Fingertips

Unlock structural insights FASTER

Hydrogen-Deuterium Exchange (HDX) is a powerful technique for studying interactions between proteins and ligands, as well as protein-protein interactions, protein stability, and structural changes. To achieve accurate and reproducible results, it is essential to ensure precise timing, maintain tight temperature control, and handle samples carefully - every time. The CHRONECT™ HDX Workstation addresses these challenges by automating your entire HDX workflow, providing you with the confidence, flexibility, and speed necessary to gain deeper insights into your proteins more quickly and confidently.

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HDX Projects Completed in Hours...Not Weeks

The NEW HDExaminer PRO, is an advanced software solution for HDX-MS data analysis. Built to eliminate manual processing and improve accuracy, it delivers fast, reliable results that accelerate your ability to identify epitopes, map binding sites, and study protein dynamics.

Trusted by leading labs & regulatory agencies

Get faster, deeper insights into protein structure

With our fully automated HDX workstation, you streamline every step from sample prep to analysis, gaining clear, reliable answers with less hands-on time. Compatible with bottom-up, middle-down, and top-down studies, it's your complete solution for protein characterization.

Flexible by Design

Configurations designed to match your needs in throughput and experimental complexity.

Precise Temperature & pH Control

Advanced cooling chambers and chilled syringes maintain optimal conditions for sample integrity and in-line digestion efficiency. Quench conditions are optimized for maximum sequence coverage.

Optimized Consumables

Trajan’s ProDx Protease columns offer low carryover and superior performance at 0°C

Confident Binding Site Insights, Fast

Automation goes beyond sample preparation. Our complete HDX solution features the NEW HDExaminer PRO software, empowering you to streamline data analysis with intuitive and efficient tools for accelerated insights

Unmatched Global Support

Trajan’s HDX experts with over 60 years of combined experience and certified service teams provide personalized training, support, and consulting globally.

Quantifiable Results

 
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15-Second Time Points

Capture rapid structural changes with time points as short as 15 seconds – ideal for dynamic protein studies and high-resolution insights.

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0°C Temperature Control

Maintain consistent low temperatures throughout the workflow to minimize back exchange and preserve sample integrity across every run.

5-times-faster

5x More Throughput

Dual-head parallel processing lets you run more replicates, proteins, and conditions delivering reliable, reproducible data up to 5x faster than manual workflows.

“Integrating the CHRONECT MOSH/MOAH workstation into our lab has been a game-changer. We’re able to handle more samples in less time, and the consistency across runs is remarkable. It’s become an essential part of our workflow for detecting mineral oil contaminants with confidence.”

— Natalie Kwan,Quality Control Director, FoodSafe Labs, Inc.

“Integrating the CHRONECT MOSH/MOAH workstation into our lab has been a game-changer. We’re able to handle more samples in less time, and the consistency across runs is remarkable. It’s become an essential part of our workflow for detecting mineral oil contaminants with confidence.”

— Natalie Kwan,Quality Control Director, FoodSafe Labs, Inc.

“Integrating the CHRONECT MOSH/MOAH workstation into our lab has been a game-changer. We’re able to handle more samples in less time, and the consistency across runs is remarkable. It’s become an essential part of our workflow for detecting mineral oil contaminants with confidence.”

— Natalie Kwan,Quality Control Director, FoodSafe Labs, Inc.

Ready to simplify HDX?

Talk to our experts to see how CHRONECT HDX helps you keep pace with pharmaceutical development and proteomic research – delivering fast, reliable, and automated protein structure and dynamics results tailored to your project goal..

Maximize your workstation Performance with expert training and ongoing support

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Service and Support

Our support team is always available to provide comprehensive guidance and support service, ensuring minimal downtime.

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Training

Available on-site or virtually, our training sessions, ensure efficient and accurate operation from day one, helping you meet your specific lab needs.

Ensuring the safety of food products is your top priority. Mineral oil hydrocarbons present serious health risks and are tightly regulated. Automated CHRONECT MOSH/MOAH workstations by Trajan enable you to…
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Eliminate manual handling and reduce variability for complex matrices
Eliminate manual handling and reduce variability for complex matrices
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