
Fully Automated HDX-MS at Your Fingertips
Unlock structural insights FASTER
Hydrogen-Deuterium Exchange (HDX) is a powerful technique for studying interactions between proteins and ligands, as well as protein-protein interactions, protein stability, and structural changes. To achieve accurate and reproducible results, it is essential to ensure precise timing, maintain tight temperature control, and handle samples carefully - every time. The CHRONECT™ HDX Workstation addresses these challenges by automating your entire HDX workflow, providing you with the confidence, flexibility, and speed necessary to gain deeper insights into your proteins more quickly and confidently.

HDX Projects Completed in Hours...Not Weeks
Trusted by leading labs & regulatory agencies





Get faster, deeper insights into protein structure
With our fully automated HDX workstation, you streamline every step from sample prep to analysis, gaining clear, reliable answers with less hands-on time. Compatible with bottom-up, middle-down, and top-down studies, it's your complete solution for protein characterization.
Configurations designed to match your needs in throughput and experimental complexity.
Advanced cooling chambers and chilled syringes maintain optimal conditions for sample integrity and in-line digestion efficiency. Quench conditions are optimized for maximum sequence coverage.
Trajan’s ProDx Protease columns offer low carryover and superior performance at 0°C
Automation goes beyond sample preparation. Our complete HDX solution features the NEW HDExaminer PRO software, empowering you to streamline data analysis with intuitive and efficient tools for accelerated insights
Trajan’s HDX experts with over 60 years of combined experience and certified service teams provide personalized training, support, and consulting globally.
Quantifiable Results

15-Second Time Points
Capture rapid structural changes with time points as short as 15 seconds – ideal for dynamic protein studies and high-resolution insights.

0°C Temperature Control
Maintain consistent low temperatures throughout the workflow to minimize back exchange and preserve sample integrity across every run.

5x More Throughput
Dual-head parallel processing lets you run more replicates, proteins, and conditions delivering reliable, reproducible data up to 5x faster than manual workflows.
“Integrating the CHRONECT MOSH/MOAH workstation into our lab has been a game-changer. We’re able to handle more samples in less time, and the consistency across runs is remarkable. It’s become an essential part of our workflow for detecting mineral oil contaminants with confidence.”
“Integrating the CHRONECT MOSH/MOAH workstation into our lab has been a game-changer. We’re able to handle more samples in less time, and the consistency across runs is remarkable. It’s become an essential part of our workflow for detecting mineral oil contaminants with confidence.”
“Integrating the CHRONECT MOSH/MOAH workstation into our lab has been a game-changer. We’re able to handle more samples in less time, and the consistency across runs is remarkable. It’s become an essential part of our workflow for detecting mineral oil contaminants with confidence.”
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Ready to simplify HDX?
Talk to our experts to see how CHRONECT HDX helps you keep pace with pharmaceutical development and proteomic research – delivering fast, reliable, and automated protein structure and dynamics results tailored to your project goal..
Maximize your workstation Performance with expert training and ongoing support
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